Myofibroblast transdifferentiation is associated with changes in cellular and extracellular vesicle miRNA abundance.

Transforming growth factor-beta 1 (TGF-β1), a pro-fibrotic tumour-derived factor promotes fibroblast differentiation in the tumour microenvironment and is thought to contribute to the development of pro-tumourigenic cancer-associated fibroblasts (CAFs) by promoting myofibroblast differentiation. miR...

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Autores principales: Siti Amalina Inche Zainal Abidin, Ian Charles Paterson, Stuart Hunt, Daniel W Lambert, Samuel Higginbotham, Ryan Charles Pink
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/5829c2c4648b4f4fb2e585c11e333e20
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