Beneficial antimicrobial effect of the addition of an aminoglycoside to a β-lactam antibiotic in an E. coli porcine intensive care severe sepsis model.

This study aimed to determine whether the addition of an aminoglycoside to a ß-lactam antibiotic increases the antimicrobial effect during the early phase of Gram-negative severe sepsis/septic shock. A porcine model was selected that considered each animal's individual blood bactericidal capaci...

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Autores principales: Paul Skorup, Lisa Maudsdotter, Miklós Lipcsey, Markus Castegren, Anders Larsson, Ann-Beth Jonsson, Jan Sjölin
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/582edccf1e8e497fb3446a6967718d63
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