Beneficial antimicrobial effect of the addition of an aminoglycoside to a β-lactam antibiotic in an E. coli porcine intensive care severe sepsis model.
This study aimed to determine whether the addition of an aminoglycoside to a ß-lactam antibiotic increases the antimicrobial effect during the early phase of Gram-negative severe sepsis/septic shock. A porcine model was selected that considered each animal's individual blood bactericidal capaci...
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Autores principales: | Paul Skorup, Lisa Maudsdotter, Miklós Lipcsey, Markus Castegren, Anders Larsson, Ann-Beth Jonsson, Jan Sjölin |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/582edccf1e8e497fb3446a6967718d63 |
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