Semi-automated closed system manufacturing of lentivirus gene-modified haematopoietic stem cells for gene therapy
Current methods for haematopoietic stem cell gene therapy are laborious and require special licensed facilities. Here the authors develop a semi-automated protocol using a commercially available device to allow for benchtop generation of gene-modified blood cell products for transplantation, that me...
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Autores principales: | Jennifer E. Adair, Timothy Waters, Kevin G. Haworth, Sara P. Kubek, Grant D. Trobridge, Jonah D. Hocum, Shelly Heimfeld, Hans-Peter Kiem |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
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Materias: | |
Acceso en línea: | https://doaj.org/article/583cfd673dbc436f8e0a56f2549b1b65 |
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