Transcriptional and Mutational Profiling of B-Other Acute Lymphoblastic Leukemia for Improved Diagnostics

Transcriptional and Mutational Profiling of B-Other Acute Lymphoblastic Leukemia for Improved Diagnostics

B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is the most common cancer in children, and significant progress has been made in diagnostics and the treatment of this disease based on the subtypes of BCP-ALL. However, in a large proportion of cases (B-other), recurrent BCP-ALL-associated gen...

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Autores principales: Philippe Chouvarine, Željko Antić, Jana Lentes, Charlotte Schröder, Julia Alten, Monika Brüggemann, Enrique Carrillo-de Santa Pau, Thomas Illig, Teresa Laguna, Denis Schewe, Martin Stanulla, Ming Tang, Martin Zimmermann, Martin Schrappe, Brigitte Schlegelberger, Gunnar Cario, Anke K. Bergmann
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
whole-transcriptome sequencing
B-cell precursor acute lymphoblastic leukemia
gene fusions
treatment stratification biomarkers
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Acceso en línea:https://doaj.org/article/5844b8801bad46869a44b4eedbef90a3
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https://doaj.org/article/5844b8801bad46869a44b4eedbef90a3

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