Novel insights into peptide amidation and amidating activity in the human circulation

Abstract C-terminal α-amidation is the final and essential step in the biosynthesis of several peptide hormones. Peptidylglycine α-amidating monooxygenase (PAM) is the only known enzyme to catalyse this reaction. PAM amidating activity (AMA) is known to be present in human circulation, but its physi...

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Autores principales: Paul Kaufmann, Andreas Bergmann, Olle Melander
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/586afca4f3564839973bd01e8926ea08
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