The imprinted gene Pw1/Peg3 regulates skeletal muscle growth, satellite cell metabolic state, and self-renewal

Abstract Pw1/Peg3 is an imprinted gene expressed from the paternally inherited allele. Several imprinted genes, including Pw1/Peg3, have been shown to regulate overall body size and play a role in adult stem cells. Pw1/Peg3 is expressed in muscle stem cells (satellite cells) as well as a progenitor...

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Autores principales: Rosa Maria Correra, David Ollitrault, Mariana Valente, Alessia Mazzola, Bjorn T. Adalsteinsson, Anne C. Ferguson-Smith, Giovanna Marazzi, David A. Sassoon
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/586cd7a187fa4bc7bf928acf22771284
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