Deficient thyroid hormone transport to the brain leads to impairments in axonal caliber and oligodendroglial development

Mutations in the thyroid hormone transporter monocarboxylate transporter 8 (MCT8) lead to profound brain alterations, including myelination impairments, in humans. We aimed to further explore the pathophysiological mechanisms underlying the MCT8 deficiency-associated myelination impairments to unrav...

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Main Authors: Víctor Valcárcel-Hernández, Daniela López-Espíndola, Marina Guillén-Yunta, Ángel García-Aldea, Inés López de Toledo Soler, Soledad Bárez-López, Ana Guadaño-Ferraz
Format: article
Language:EN
Published: Elsevier 2022
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Online Access:https://doaj.org/article/589a1f6799c14691a43c1635754f92f2
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