Heregulin Activity Assays for Residual Testing of Cell Therapy Products

Abstract Background Heregulin is a ligand for the protooncogene product ErbB/HER that acts as  a key mitogenic factor for human Schwann cells (hSCs). Heregulin is required for sustained hSC growth in vitro but must be thoroughly removed before cell collection for transplantation due to potential saf...

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Autores principales: Paula V. Monje, Ketty Bacallao, Gabriela I. Aparicio, Anil Lalwani
Formato: article
Lenguaje:EN
Publicado: BMC 2021
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Acceso en línea:https://doaj.org/article/58a034fad7b24306836d56db96b3ce90
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