Gene expression profiling specifies chemokine, mitochondrial and lipid metabolism signatures in leprosy.

Gene expression profiling specifies chemokine, mitochondrial and lipid metabolism signatures in leprosy.

Herein, we performed microarray experiments in Schwann cells infected with live M. leprae and identified novel differentially expressed genes (DEG) in M. leprae infected cells. Also, we selected candidate genes associated or implicated with leprosy in genetic studies and biological experiments. Fort...

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Autores principales: Luana Tatiana Albuquerque Guerreiro, Anna Beatriz Robottom-Ferreira, Marcelo Ribeiro-Alves, Thiago Gomes Toledo-Pinto, Tiana Rosa Brito, Patrícia Sammarco Rosa, Felipe Galvan Sandoval, Márcia Rodrigues Jardim, Sérgio Gomes Antunes, Edward J Shannon, Euzenir Nunes Sarno, Maria Cristina Vidal Pessolani, Diana Lynn Williams, Milton Ozório Moraes
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/58cb7e797f8b4d1ab03913facd9c320a
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https://doaj.org/article/58cb7e797f8b4d1ab03913facd9c320a

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