Dopamine, sleep, and neuronal excitability modulate amyloid-β-mediated forgetting in Drosophila.

Alzheimer disease (AD) is one of the main causes of age-related dementia and neurodegeneration. However, the onset of the disease and the mechanisms causing cognitive defects are not well understood. Aggregation of amyloidogenic peptides is a pathological hallmark of AD and is assumed to be a centra...

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Auteurs principaux: Jenifer C Kaldun, Shahnaz R Lone, Ana M Humbert Camps, Cornelia Fritsch, Yves F Widmer, Jens V Stein, Seth M Tomchik, Simon G Sprecher
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2021
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Accès en ligne:https://doaj.org/article/58cca99fbadd4f4a824ce76c47662ce6
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