Dopamine, sleep, and neuronal excitability modulate amyloid-β-mediated forgetting in Drosophila.
Alzheimer disease (AD) is one of the main causes of age-related dementia and neurodegeneration. However, the onset of the disease and the mechanisms causing cognitive defects are not well understood. Aggregation of amyloidogenic peptides is a pathological hallmark of AD and is assumed to be a centra...
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Main Authors: | Jenifer C Kaldun, Shahnaz R Lone, Ana M Humbert Camps, Cornelia Fritsch, Yves F Widmer, Jens V Stein, Seth M Tomchik, Simon G Sprecher |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2021
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Online Access: | https://doaj.org/article/58cca99fbadd4f4a824ce76c47662ce6 |
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