Hippocampal clock regulates memory retrieval via Dopamine and PKA-induced GluA1 phosphorylation

Hippocampal clock regulates memory retrieval via Dopamine and PKA-induced GluA1 phosphorylation

The neural mechanisms that lead to a relative deficit in memory retrieval in the afternoon are unclear. Here, the authors show that the circadian - dependent transcription factor BMAL1 regulates retrieval through dopamine and glutamate receptor phosphorylation.

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Autores principales: Shunsuke Hasegawa, Hotaka Fukushima, Hiroshi Hosoda, Tatsurou Serita, Rie Ishikawa, Tomohiro Rokukawa, Ryouka Kawahara-Miki, Yue Zhang, Miho Ohta, Shintaro Okada, Toshiyuki Tanimizu, Sheena A. Josselyn, Paul W. Frankland, Satoshi Kida
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/58cfaf7133c44f2abb529a34f9248cd2
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https://doaj.org/article/58cfaf7133c44f2abb529a34f9248cd2

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