Hippocampal clock regulates memory retrieval via Dopamine and PKA-induced GluA1 phosphorylation
The neural mechanisms that lead to a relative deficit in memory retrieval in the afternoon are unclear. Here, the authors show that the circadian - dependent transcription factor BMAL1 regulates retrieval through dopamine and glutamate receptor phosphorylation.
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Nature Portfolio
2019
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oai:doaj.org-article:58cfaf7133c44f2abb529a34f9248cd22021-12-02T14:38:44ZHippocampal clock regulates memory retrieval via Dopamine and PKA-induced GluA1 phosphorylation10.1038/s41467-019-13554-y2041-1723https://doaj.org/article/58cfaf7133c44f2abb529a34f9248cd22019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13554-yhttps://doaj.org/toc/2041-1723The neural mechanisms that lead to a relative deficit in memory retrieval in the afternoon are unclear. Here, the authors show that the circadian - dependent transcription factor BMAL1 regulates retrieval through dopamine and glutamate receptor phosphorylation.Shunsuke HasegawaHotaka FukushimaHiroshi HosodaTatsurou SeritaRie IshikawaTomohiro RokukawaRyouka Kawahara-MikiYue ZhangMiho OhtaShintaro OkadaToshiyuki TanimizuSheena A. JosselynPaul W. FranklandSatoshi KidaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019) |
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EN |
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Science Q |
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Science Q Shunsuke Hasegawa Hotaka Fukushima Hiroshi Hosoda Tatsurou Serita Rie Ishikawa Tomohiro Rokukawa Ryouka Kawahara-Miki Yue Zhang Miho Ohta Shintaro Okada Toshiyuki Tanimizu Sheena A. Josselyn Paul W. Frankland Satoshi Kida Hippocampal clock regulates memory retrieval via Dopamine and PKA-induced GluA1 phosphorylation |
description |
The neural mechanisms that lead to a relative deficit in memory retrieval in the afternoon are unclear. Here, the authors show that the circadian - dependent transcription factor BMAL1 regulates retrieval through dopamine and glutamate receptor phosphorylation. |
format |
article |
author |
Shunsuke Hasegawa Hotaka Fukushima Hiroshi Hosoda Tatsurou Serita Rie Ishikawa Tomohiro Rokukawa Ryouka Kawahara-Miki Yue Zhang Miho Ohta Shintaro Okada Toshiyuki Tanimizu Sheena A. Josselyn Paul W. Frankland Satoshi Kida |
author_facet |
Shunsuke Hasegawa Hotaka Fukushima Hiroshi Hosoda Tatsurou Serita Rie Ishikawa Tomohiro Rokukawa Ryouka Kawahara-Miki Yue Zhang Miho Ohta Shintaro Okada Toshiyuki Tanimizu Sheena A. Josselyn Paul W. Frankland Satoshi Kida |
author_sort |
Shunsuke Hasegawa |
title |
Hippocampal clock regulates memory retrieval via Dopamine and PKA-induced GluA1 phosphorylation |
title_short |
Hippocampal clock regulates memory retrieval via Dopamine and PKA-induced GluA1 phosphorylation |
title_full |
Hippocampal clock regulates memory retrieval via Dopamine and PKA-induced GluA1 phosphorylation |
title_fullStr |
Hippocampal clock regulates memory retrieval via Dopamine and PKA-induced GluA1 phosphorylation |
title_full_unstemmed |
Hippocampal clock regulates memory retrieval via Dopamine and PKA-induced GluA1 phosphorylation |
title_sort |
hippocampal clock regulates memory retrieval via dopamine and pka-induced glua1 phosphorylation |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/58cfaf7133c44f2abb529a34f9248cd2 |
work_keys_str_mv |
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1718390896152543232 |