B cell deficient mice are protected from biliary obstruction in the rotavirus-induced mouse model of biliary atresia.
A leading theory regarding the pathogenesis of biliary atresia (BA) is that bile duct injury is initiated by a virus infection, followed by an autoimmune response targeting bile ducts. In experimental models of autoimmune diseases, B cells have been shown to play an important role. The aim of this s...
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Autores principales: | , , , , |
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Formato: | article |
Lenguaje: | EN |
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Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/590002222cf24d0891dae1ce4907c617 |
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