B cell deficient mice are protected from biliary obstruction in the rotavirus-induced mouse model of biliary atresia.

A leading theory regarding the pathogenesis of biliary atresia (BA) is that bile duct injury is initiated by a virus infection, followed by an autoimmune response targeting bile ducts. In experimental models of autoimmune diseases, B cells have been shown to play an important role. The aim of this s...

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Autores principales: Amy G Feldman, Rebecca M Tucker, Erika K Fenner, Roberta Pelanda, Cara L Mack
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/590002222cf24d0891dae1ce4907c617
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