B cell deficient mice are protected from biliary obstruction in the rotavirus-induced mouse model of biliary atresia.
A leading theory regarding the pathogenesis of biliary atresia (BA) is that bile duct injury is initiated by a virus infection, followed by an autoimmune response targeting bile ducts. In experimental models of autoimmune diseases, B cells have been shown to play an important role. The aim of this s...
Guardado en:
Autores principales: | Amy G Feldman, Rebecca M Tucker, Erika K Fenner, Roberta Pelanda, Cara L Mack |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
|
Materias: | |
Acceso en línea: | https://doaj.org/article/590002222cf24d0891dae1ce4907c617 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Rotavirus Infection and Cytopathogenesis in Human Biliary Organoids Potentially Recapitulate Biliary Atresia Development
por: Sunrui Chen, et al.
Publicado: (2020) -
Biliary atresia-specific deciduous pulp stem cells feature biliary deficiency
por: Soichiro Sonoda, et al.
Publicado: (2021) -
Biliary atresia: the Brazilian experience
por: De Carvalho,Elisa, et al.
Publicado: (2012) -
Biliary Atresia – emerging diagnostic and therapy opportunities
por: Urban Lendahl, et al.
Publicado: (2021) -
Mitochondrial Mutations in Cholestatic Liver Disease with Biliary Atresia
por: Hong Koh, et al.
Publicado: (2018)