De-escalation antibiotic therapy alleviates organ injury through modulation of NETs formation during sepsis

Abstract Empiric broad-spectrum antimicrobials therapy is suggested to be started immediately for sepsis patients. Empiric antimicrobial therapy should be narrowed once pathogen identification and sensitivities are established. However, the detailed mechanisms of de-escalation strategy are still unc...

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Autores principales: Zehua Duan, Tian Xie, Chengnan Chu, Fang Chen, Xinyu Wang, Jieshou Li, Weiwei Ding
Formato: article
Lenguaje:EN
Publicado: Nature Publishing Group 2021
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Acceso en línea:https://doaj.org/article/591756b817a645679e99147ab43f9efa
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