Glial cell-line derived neurotrophic factor protects human islets from nutrient deprivation and endoplasmic reticulum stress induced apoptosis

Abstract One of the key limitations to successful human islet transplantation is loss of islets due to stress responses pre- and post-transplantation. Nutrient deprivation and ER stress have been identified as important mechanisms leading to apoptosis. Glial Cell-line Derived Neurotrophic Factor (GD...

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Bibliographic Details
Main Authors: Shadab Abadpour, Sven O. Göpel, Simen W. Schive, Olle Korsgren, Aksel Foss, Hanne Scholz
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/591c132f028b437a887c73c5885b89cb
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