Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria
The antibiotic vancomycin inhibits bacterial cell wall synthesis by binding to a membrane-associated precursor. Here, Blaskovich et al. synthesize vancomycin derivatives containing lipophilic peptide moieties that enhance membrane affinity and in vivo activities against glycopeptide-resistant strain...
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Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Acceso en línea: | https://doaj.org/article/5939bc54d4b347d7b1b16946d6d5c490 |
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