RNA Binding Motif Protein RBM45 Regulates Expression of the 11-Kilodalton Protein of Parvovirus B19 through Binding to Novel Intron Splicing Enhancers

ABSTRACT During infection of human parvovirus B19 (B19V), one viral precursor mRNA (pre-mRNA) is transcribed by a single promoter and is alternatively spliced and alternatively polyadenylated. Here, we identified a novel cis-acting sequence (5′-GUA AAG CUA CGG GAC GGU-3′), intronic splicing enhancer...

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Bibliographic Details
Main Authors: Jianke Wang, Safder S. Ganaie, Fang Cheng, Peng Xu, Kang Ning, Xiaomei Wang, Steve Kleiboeker, Shipeng Cheng, Jianming Qiu
Format: article
Language:EN
Published: American Society for Microbiology 2020
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Online Access:https://doaj.org/article/595f2a16c68e472bb93fb36f2f913021
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