Solid-state NMR spectroscopy based atomistic view of a membrane protein unfolding pathway

Studying the unfolding of membrane proteins in a native-like lipid environment is challenging. Here the authors describe a method combining hydrogen-deuterium exchange and solid-state NMR measurements that allows the characterization of unfolding events in lipid-embedded membrane proteins and use th...

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Auteurs principaux: Peng Xiao, David Bolton, Rachel A. Munro, Leonid S. Brown, Vladimir Ladizhansky
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/598def11c2fc4bcd97e663bc018acd2a
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