The translational landscape of ground state pluripotency

Translational control of gene expression can lead to significant divergence between mRNA and protein abundance. Here, the authors describe transcriptional rewiring and translational buffering during transition from naïve to primed pluripotency through quantitation of mRNA-abundance, translation rate...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Yaser Atlasi, Seyed Mehdi Jafarnejad, Christos G. Gkogkas, Michiel Vermeulen, Nahum Sonenberg, Hendrik G. Stunnenberg
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Q
Acceso en línea:https://doaj.org/article/5995ba7b3371459d9c0c5530ed92ef7b
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
Descripción
Sumario:Translational control of gene expression can lead to significant divergence between mRNA and protein abundance. Here, the authors describe transcriptional rewiring and translational buffering during transition from naïve to primed pluripotency through quantitation of mRNA-abundance, translation rate and protein expression.