The translational landscape of ground state pluripotency

Translational control of gene expression can lead to significant divergence between mRNA and protein abundance. Here, the authors describe transcriptional rewiring and translational buffering during transition from naïve to primed pluripotency through quantitation of mRNA-abundance, translation rate...

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Autores principales:	Yaser Atlasi, Seyed Mehdi Jafarnejad, Christos G. Gkogkas, Michiel Vermeulen, Nahum Sonenberg, Hendrik G. Stunnenberg
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5995ba7b3371459d9c0c5530ed92ef7b
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spelling	oai:doaj.org-article:5995ba7b3371459d9c0c5530ed92ef7b2021-12-02T17:31:40ZThe translational landscape of ground state pluripotency10.1038/s41467-020-15449-92041-1723https://doaj.org/article/5995ba7b3371459d9c0c5530ed92ef7b2020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15449-9https://doaj.org/toc/2041-1723Translational control of gene expression can lead to significant divergence between mRNA and protein abundance. Here, the authors describe transcriptional rewiring and translational buffering during transition from naïve to primed pluripotency through quantitation of mRNA-abundance, translation rate and protein expression.Yaser AtlasiSeyed Mehdi JafarnejadChristos G. GkogkasMichiel VermeulenNahum SonenbergHendrik G. StunnenbergNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yaser Atlasi Seyed Mehdi Jafarnejad Christos G. Gkogkas Michiel Vermeulen Nahum Sonenberg Hendrik G. Stunnenberg The translational landscape of ground state pluripotency
description	Translational control of gene expression can lead to significant divergence between mRNA and protein abundance. Here, the authors describe transcriptional rewiring and translational buffering during transition from naïve to primed pluripotency through quantitation of mRNA-abundance, translation rate and protein expression.
format	article
author	Yaser Atlasi Seyed Mehdi Jafarnejad Christos G. Gkogkas Michiel Vermeulen Nahum Sonenberg Hendrik G. Stunnenberg
author_facet	Yaser Atlasi Seyed Mehdi Jafarnejad Christos G. Gkogkas Michiel Vermeulen Nahum Sonenberg Hendrik G. Stunnenberg
author_sort	Yaser Atlasi
title	The translational landscape of ground state pluripotency
title_short	The translational landscape of ground state pluripotency
title_full	The translational landscape of ground state pluripotency
title_fullStr	The translational landscape of ground state pluripotency
title_full_unstemmed	The translational landscape of ground state pluripotency
title_sort	translational landscape of ground state pluripotency
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/5995ba7b3371459d9c0c5530ed92ef7b
work_keys_str_mv	AT yaseratlasi thetranslationallandscapeofgroundstatepluripotency AT seyedmehdijafarnejad thetranslationallandscapeofgroundstatepluripotency AT christosggkogkas thetranslationallandscapeofgroundstatepluripotency AT michielvermeulen thetranslationallandscapeofgroundstatepluripotency AT nahumsonenberg thetranslationallandscapeofgroundstatepluripotency AT hendrikgstunnenberg thetranslationallandscapeofgroundstatepluripotency AT yaseratlasi translationallandscapeofgroundstatepluripotency AT seyedmehdijafarnejad translationallandscapeofgroundstatepluripotency AT christosggkogkas translationallandscapeofgroundstatepluripotency AT michielvermeulen translationallandscapeofgroundstatepluripotency AT nahumsonenberg translationallandscapeofgroundstatepluripotency AT hendrikgstunnenberg translationallandscapeofgroundstatepluripotency
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The translational landscape of ground state pluripotency

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