Cancer-associated noncoding mutations affect RNA G-quadruplex-mediated regulation of gene expression

Abstract Cancer is a multifactorial disease driven by a combination of genetic and environmental factors. Many cancer driver mutations have been characterised in protein-coding regions of the genome. However, mutations in noncoding regions associated with cancer have been less investigated. G-quadru...

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Autores principales: Mahdi Zeraati, Aaron L. Moye, Jason W. H. Wong, Dilmi Perera, Mark J. Cowley, Daniel U. Christ, Tracy M. Bryan, Marcel E. Dinger
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/59ab4a1d4af84fbd87536aa985af8b63
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