Microcirculatory Function during Endotoxemia—A Functional Citrulline-Arginine-NO Pathway and NOS3 Complex Is Essential to Maintain the Microcirculation
Competition for the amino acid arginine by endothelial nitric-oxide synthase (NOS3) and (pro-)inflammatory NO-synthase (NOS2) during endotoxemia appears essential in the derangement of the microcirculatory flow. This study investigated the role of NOS2 and NOS3 combined with/without citrulline suppl...
Enregistré dans:
Auteurs principaux: | Karolina A. P. Wijnands, Dennis M. Meesters, Benjamin Vandendriessche, Jacob J. Briedé, Hans M. H. van Eijk, Peter Brouckaert, Anje Cauwels, Wouter H. Lamers, Martijn Poeze |
---|---|
Format: | article |
Langue: | EN |
Publié: |
MDPI AG
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/59bd5394c46a4b4b917d5de6f091e85c |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Citrulline Accumulation Mechanism of Pediococcus acidilactici and Weissella confusa in Soy Sauce and the Effects of Phenolic Compound on Citrulline Accumulation
par: Kai Zhou, et autres
Publié: (2021) - Microcirculation
-
Remimazolam Protects Against LPS-Induced Endotoxicity Improving Survival of Endotoxemia Mice
par: Xiaolei Liu, et autres
Publié: (2021) -
Pioglitazone Ameliorates Acute Endotoxemia-Induced Acute on Chronic Renal Dysfunction in Cirrhotic Ascitic Rats
par: Szu-Yu Liu, et autres
Publié: (2021) -
Burkholderia pseudomallei-loaded cells act as a Trojan horse to invade the brain during endotoxemia
par: Pei-Tan Hsueh, et autres
Publié: (2018)