The rs2304256 Polymorphism in Gene Is Associated with Protection for Type 1 Diabetes Mellitus

Background Tyrosine kinase 2 (TYK2) is a candidate gene for type 1 diabetes mellitus (T1DM) since it plays an important role in regulating apoptotic and pro-inflammatory pathways in pancreatic β-cells through modulation of the type I interferon signaling pathway. The rs2304256 single nucleotide poly...

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Auteurs principaux: Felipe Mateus Pellenz, Cristine Dieter, Guilherme Coutinho Kullmann Duarte, Luís Henrique Canani, Bianca Marmontel de Souza, Daisy Crispim
Format: article
Langue:EN
Publié: Korean Diabetes Association 2021
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Accès en ligne:https://doaj.org/article/59e0aef457504c18868543cf88ef3278
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