A viral microRNA cluster strongly potentiates the transforming properties of a human herpesvirus.
Epstein-Barr virus (EBV), an oncogenic human herpesvirus, induces cell proliferation after infection of resting B lymphocytes, its reservoir in vivo. The viral latent proteins are necessary for permanent B cell growth, but it is unknown whether they are sufficient. EBV was recently found to encode m...
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Main Authors: | Regina Feederle, Sarah D Linnstaedt, Helmut Bannert, Helge Lips, Maja Bencun, Bryan R Cullen, Henri-Jacques Delecluse |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2011
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Online Access: | https://doaj.org/article/59e276d0317c489facca6687335d414f |
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