Effective in vivo treatment of acute lung injury with helical, amphipathic peptoid mimics of pulmonary surfactant proteins

Abstract Acute lung injury (ALI) leads to progressive loss of breathing capacity and hypoxemia, as well as pulmonary surfactant dysfunction. ALI’s pathogenesis and management are complex, and it is a significant cause of morbidity and mortality worldwide. Exogenous surfactant therapy, even for resea...

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Autores principales: Ann M. Czyzewski, Lynda M. McCaig, Michelle T. Dohm, Lauren A. Broering, Li-Juan Yao, Nathan J. Brown, Maruti K. Didwania, Jennifer S. Lin, Jim F. Lewis, Ruud Veldhuizen, Annelise E. Barron
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/5a096b460ffa43f2a9f1d30deb079393
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