Humanized single domain antibodies neutralize SARS-CoV-2 by targeting the spike receptor binding domain
Here, using a humanized phage display library with recombinant SARS- CoV-2 receptor binding domain (RBD) proteins, the authors identify a number of single domain antibodies (sdAbs) that neutralize SARS-CoV-2 in vitro by inhibiting the interaction of the RDB with the host entry receptor ACE2.
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2020
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/5a2adb117bc54fe7a3edefdf76d0df98 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|