The effect of hypoxia on PD-L1 expression in bladder cancer

Abstract Introduction Recent data has demonstrated that hypoxia drives an immunosuppressive tumour microenvironment (TME) via various mechanisms including hypoxia inducible factor (HIF)-dependent upregulation of programmed death ligand 1 (PD-L1). Both hypoxia and an immunosuppressive TME are targeta...

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Autores principales: Vicky Smith, Debayan Mukherjee, Sapna Lunj, Ananya Choudhury, Peter Hoskin, Catharine West, Tim Illidge
Formato: article
Lenguaje:EN
Publicado: BMC 2021
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HIF
Acceso en línea:https://doaj.org/article/5a3b699691944cdba47478b8e3d7583a
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