The effect of hypoxia on PD-L1 expression in bladder cancer

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The effect of hypoxia on PD-L1 expression in bladder cancer

Abstract Introduction Recent data has demonstrated that hypoxia drives an immunosuppressive tumour microenvironment (TME) via various mechanisms including hypoxia inducible factor (HIF)-dependent upregulation of programmed death ligand 1 (PD-L1). Both hypoxia and an immunosuppressive TME are targeta...

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Autores principales:	Vicky Smith, Debayan Mukherjee, Sapna Lunj, Ananya Choudhury, Peter Hoskin, Catharine West, Tim Illidge
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	hypoxia HIF PD-L1 Tumour microenvironment Immunosuppression TIME Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/5a3b699691944cdba47478b8e3d7583a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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