A novel canine reference genome resolves genomic architecture and uncovers transcript complexity

Here, the authors report an improved de novo reference genome for the domestic dog based on a female German Shepherd named Mischka. The new genome increases contiguity 55-fold over the previous dog assembly and uncovers functional elements that were not previously identifiable.

Guardado en:
Detalles Bibliográficos
Autores principales: Chao Wang, Ola Wallerman, Maja-Louise Arendt, Elisabeth Sundström, Åsa Karlsson, Jessika Nordin, Suvi Mäkeläinen, Gerli Rosengren Pielberg, Jeanette Hanson, Åsa Ohlsson, Sara Saellström, Henrik Rönnberg, Ingrid Ljungvall, Jens Häggström, Tomas F. Bergström, Åke Hedhammar, Jennifer R. S. Meadows, Kerstin Lindblad-Toh
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Acceso en línea:https://doaj.org/article/5a3f7ff195854c04a2ed28f879d96bac
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:5a3f7ff195854c04a2ed28f879d96bac
record_format dspace
spelling oai:doaj.org-article:5a3f7ff195854c04a2ed28f879d96bac2021-12-02T14:11:03ZA novel canine reference genome resolves genomic architecture and uncovers transcript complexity10.1038/s42003-021-01698-x2399-3642https://doaj.org/article/5a3f7ff195854c04a2ed28f879d96bac2021-02-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01698-xhttps://doaj.org/toc/2399-3642Here, the authors report an improved de novo reference genome for the domestic dog based on a female German Shepherd named Mischka. The new genome increases contiguity 55-fold over the previous dog assembly and uncovers functional elements that were not previously identifiable.Chao WangOla WallermanMaja-Louise ArendtElisabeth SundströmÅsa KarlssonJessika NordinSuvi MäkeläinenGerli Rosengren PielbergJeanette HansonÅsa OhlssonSara SaellströmHenrik RönnbergIngrid LjungvallJens HäggströmTomas F. BergströmÅke HedhammarJennifer R. S. MeadowsKerstin Lindblad-TohNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Chao Wang
Ola Wallerman
Maja-Louise Arendt
Elisabeth Sundström
Åsa Karlsson
Jessika Nordin
Suvi Mäkeläinen
Gerli Rosengren Pielberg
Jeanette Hanson
Åsa Ohlsson
Sara Saellström
Henrik Rönnberg
Ingrid Ljungvall
Jens Häggström
Tomas F. Bergström
Åke Hedhammar
Jennifer R. S. Meadows
Kerstin Lindblad-Toh
A novel canine reference genome resolves genomic architecture and uncovers transcript complexity
description Here, the authors report an improved de novo reference genome for the domestic dog based on a female German Shepherd named Mischka. The new genome increases contiguity 55-fold over the previous dog assembly and uncovers functional elements that were not previously identifiable.
format article
author Chao Wang
Ola Wallerman
Maja-Louise Arendt
Elisabeth Sundström
Åsa Karlsson
Jessika Nordin
Suvi Mäkeläinen
Gerli Rosengren Pielberg
Jeanette Hanson
Åsa Ohlsson
Sara Saellström
Henrik Rönnberg
Ingrid Ljungvall
Jens Häggström
Tomas F. Bergström
Åke Hedhammar
Jennifer R. S. Meadows
Kerstin Lindblad-Toh
author_facet Chao Wang
Ola Wallerman
Maja-Louise Arendt
Elisabeth Sundström
Åsa Karlsson
Jessika Nordin
Suvi Mäkeläinen
Gerli Rosengren Pielberg
Jeanette Hanson
Åsa Ohlsson
Sara Saellström
Henrik Rönnberg
Ingrid Ljungvall
Jens Häggström
Tomas F. Bergström
Åke Hedhammar
Jennifer R. S. Meadows
Kerstin Lindblad-Toh
author_sort Chao Wang
title A novel canine reference genome resolves genomic architecture and uncovers transcript complexity
title_short A novel canine reference genome resolves genomic architecture and uncovers transcript complexity
title_full A novel canine reference genome resolves genomic architecture and uncovers transcript complexity
title_fullStr A novel canine reference genome resolves genomic architecture and uncovers transcript complexity
title_full_unstemmed A novel canine reference genome resolves genomic architecture and uncovers transcript complexity
title_sort novel canine reference genome resolves genomic architecture and uncovers transcript complexity
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/5a3f7ff195854c04a2ed28f879d96bac
work_keys_str_mv AT chaowang anovelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT olawallerman anovelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT majalouisearendt anovelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT elisabethsundstrom anovelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT asakarlsson anovelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT jessikanordin anovelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT suvimakelainen anovelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT gerlirosengrenpielberg anovelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT jeanettehanson anovelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT asaohlsson anovelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT sarasaellstrom anovelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT henrikronnberg anovelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT ingridljungvall anovelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT jenshaggstrom anovelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT tomasfbergstrom anovelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT akehedhammar anovelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT jenniferrsmeadows anovelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT kerstinlindbladtoh anovelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT chaowang novelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT olawallerman novelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT majalouisearendt novelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT elisabethsundstrom novelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT asakarlsson novelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT jessikanordin novelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT suvimakelainen novelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT gerlirosengrenpielberg novelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT jeanettehanson novelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT asaohlsson novelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT sarasaellstrom novelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT henrikronnberg novelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT ingridljungvall novelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT jenshaggstrom novelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT tomasfbergstrom novelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT akehedhammar novelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT jenniferrsmeadows novelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
AT kerstinlindbladtoh novelcaninereferencegenomeresolvesgenomicarchitectureanduncoverstranscriptcomplexity
_version_ 1718391843096363008