Inhibition of RPS6K reveals context-dependent Akt activity in luminal breast cancer cells.

Aberrant signaling through insulin (Ins) and insulin-like growth factor I (IGF1) receptors contribute to the risk and advancement of many cancer types by activating cell survival cascades. Similarities between these pathways have thus far prevented the development of pharmacological interventions th...

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Auteurs principaux: Cemal Erdem, Adrian V Lee, D Lansing Taylor, Timothy R Lezon
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2021
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Accès en ligne:https://doaj.org/article/5a50932ee04e4320af6e668981cb0eb3
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