T cell-intrinsic IL-1R signaling licenses effector cytokine production by memory CD4 T cells
CD4 T cell polarizations and functions are regulated by cytokines from innate cells. Here the authors show that IL-1 deficiency does not impair the differentiation of Th1, Th2 and Th17, but IL-1 signaling is required for maintaining the expressions of their respective key cytokines to ‘license’ the...
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Autores principales: | Aakanksha Jain, Ran Song, Edward K. Wakeland, Chandrashekhar Pasare |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/5a633d6c97f64ce594f648e00b0e6574 |
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