Apoptosis inducing effect of plumbagin on colonic cancer cells depends on expression of COX-2.

Plumbagin, a quinonoid found in the plants of the Plumbaginaceae, possesses medicinal properties. In this study we investigated the anti-proliferative and apoptotic activity of plumbagin by using two human colonic cancer cell lines, HT29 and HCT15. IC50 of Plumbagin for HCT15 and HT29 cells (22.5 µM...

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Autores principales: Bharathi Raja Subramaniya, Gayathri Srinivasan, Sakeena Sadullah Mohammed Sadullah, Nimitha Davis, Lakshmi Baddi Reddi Subhadara, Devaraj Halagowder, Niranjali Devaraj Sivasitambaram
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/5a92a9869cac466387701e050bdfdf7d
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