Trimetazidine ameliorates sunitinib-induced cardiotoxicity in mice via the AMPK/mTOR/autophagy pathway
Context: Sunitinib (SU) is a multi-targeted tyrosine kinase inhibitor anticancer agent whose clinical use is often limited by cardiovascular complications. Trimetazidine (TMZ) is an anti-angina agent that has been demonstrated cardioprotective effects in numerous cardiovascular conditions, but its p...
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Autores principales: | , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Taylor & Francis Group
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/5ad1ba90404b445aadedc190f4a54bdf |
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