EB1 recognizes the nucleotide state of tubulin in the microtubule lattice.

Plus-end-tracking proteins (+TIPs) are localized at the fast-growing, or plus end, of microtubules, and link microtubule ends to cellular structures. One of the best studied +TIPs is EB1, which forms comet-like structures at the tips of growing microtubules. The molecular mechanisms by which EB1 rec...

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Autores principales: Marija Zanic, Jeffrey H Stear, Anthony A Hyman, Jonathon Howard
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
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Acceso en línea:https://doaj.org/article/5ae4942f90084a0f96426dfb79874ee8
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