Cases and distribution of visceral leishmaniasis in western São Paulo: A neglected disease in this region of Brazil.

Visceral leishmaniasis (VL) is one of the most prevalent parasitic diseases worldwide. In 2019, 97% of the total numbers of cases in Latin America were reported in Brazil. In São Paulo state, currently 17.6% of infected individuals live in the western region. To study this neglected disease on a reg...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Regiane Soares Santana, Karina Briguenti Souza, Fernanda Lussari, Elivelton Silva Fonseca, Cristiane Oliveira Andrade, Marcia Mitiko Kaihara Meidas, Lourdes Aparecida Zampieri D'Andrea, Francisco Assis Silva, Edilson Ferreira Flores, Ivete Rocha Anjolete, Luiz Euribel Prestes-Carneiro
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270
Acceso en línea:	https://doaj.org/article/5b19825ece1b47bb82846c45e888a0c5
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:5b19825ece1b47bb82846c45e888a0c5
record_format	dspace
spelling	oai:doaj.org-article:5b19825ece1b47bb82846c45e888a0c52021-11-25T06:31:46ZCases and distribution of visceral leishmaniasis in western São Paulo: A neglected disease in this region of Brazil.1935-27271935-273510.1371/journal.pntd.0009411https://doaj.org/article/5b19825ece1b47bb82846c45e888a0c52021-06-01T00:00:00Zhttps://doi.org/10.1371/journal.pntd.0009411https://doaj.org/toc/1935-2727https://doaj.org/toc/1935-2735Visceral leishmaniasis (VL) is one of the most prevalent parasitic diseases worldwide. In 2019, 97% of the total numbers of cases in Latin America were reported in Brazil. In São Paulo state, currently 17.6% of infected individuals live in the western region. To study this neglected disease on a regional scale, we describe the spread of VL in 45 municipalities of the Regional Network for Health Assistance11(RNHA11). Environmental, human VL (HVL), and canine VL (CVL) cases, Human Development Index, and Lutzomyia longipalpis databases were obtained from public agencies. Global Moran's I index and local indicators of spatial association (LISA) statistics were used to identify spatial autocorrelation and to generate maps for the identification of VL clusters. On a local scale, we determined the spread of VL in the city of Teodoro Sampaio, part of the Pontal of Paranapanema. In Teodoro Sampaio, monthly peri-domicile sand fly collection; ELISA, IFAT and Rapid Test serological CVL; and ELISA HVL serum surveys were carried out. In RNHA11 from 2000 to 2018, Lu. longipalpis was found in 77.8%, CVL in 69%, and HVL in 42.2% of the 45 municipalities, and 537 individuals were notified with HVL. Dispersion occurred from the epicenter in the north to Teodoro Sampaio, in the south, where Lu. longipalpis and CVL were found in 2010, HVL in 2018, and critical hotspots of CVL were found in the periphery. Moran's Global Index showed a weak but statistically significant spatial autocorrelation related to cases of CVL (I = 0.2572), and 11 municipalities were identified as priority areas for implementing surveillance and control actions. In RNHA11, a complex array of socioeconomic and environmental factors may be fueling the epidemic and sustaining endemic transmission of VL, adding to the study of a neglected disease in a region of São Paulo, Brazil.Regiane Soares SantanaKarina Briguenti SouzaFernanda LussariElivelton Silva FonsecaCristiane Oliveira AndradeMarcia Mitiko Kaihara MeidasLourdes Aparecida Zampieri D'AndreaFrancisco Assis SilvaEdilson Ferreira FloresIvete Rocha AnjoleteLuiz Euribel Prestes-CarneiroPublic Library of Science (PLoS)articleArctic medicine. Tropical medicineRC955-962Public aspects of medicineRA1-1270ENPLoS Neglected Tropical Diseases, Vol 15, Iss 6, p e0009411 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270
spellingShingle	Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Regiane Soares Santana Karina Briguenti Souza Fernanda Lussari Elivelton Silva Fonseca Cristiane Oliveira Andrade Marcia Mitiko Kaihara Meidas Lourdes Aparecida Zampieri D'Andrea Francisco Assis Silva Edilson Ferreira Flores Ivete Rocha Anjolete Luiz Euribel Prestes-Carneiro Cases and distribution of visceral leishmaniasis in western São Paulo: A neglected disease in this region of Brazil.
description	Visceral leishmaniasis (VL) is one of the most prevalent parasitic diseases worldwide. In 2019, 97% of the total numbers of cases in Latin America were reported in Brazil. In São Paulo state, currently 17.6% of infected individuals live in the western region. To study this neglected disease on a regional scale, we describe the spread of VL in 45 municipalities of the Regional Network for Health Assistance11(RNHA11). Environmental, human VL (HVL), and canine VL (CVL) cases, Human Development Index, and Lutzomyia longipalpis databases were obtained from public agencies. Global Moran's I index and local indicators of spatial association (LISA) statistics were used to identify spatial autocorrelation and to generate maps for the identification of VL clusters. On a local scale, we determined the spread of VL in the city of Teodoro Sampaio, part of the Pontal of Paranapanema. In Teodoro Sampaio, monthly peri-domicile sand fly collection; ELISA, IFAT and Rapid Test serological CVL; and ELISA HVL serum surveys were carried out. In RNHA11 from 2000 to 2018, Lu. longipalpis was found in 77.8%, CVL in 69%, and HVL in 42.2% of the 45 municipalities, and 537 individuals were notified with HVL. Dispersion occurred from the epicenter in the north to Teodoro Sampaio, in the south, where Lu. longipalpis and CVL were found in 2010, HVL in 2018, and critical hotspots of CVL were found in the periphery. Moran's Global Index showed a weak but statistically significant spatial autocorrelation related to cases of CVL (I = 0.2572), and 11 municipalities were identified as priority areas for implementing surveillance and control actions. In RNHA11, a complex array of socioeconomic and environmental factors may be fueling the epidemic and sustaining endemic transmission of VL, adding to the study of a neglected disease in a region of São Paulo, Brazil.
format	article
author	Regiane Soares Santana Karina Briguenti Souza Fernanda Lussari Elivelton Silva Fonseca Cristiane Oliveira Andrade Marcia Mitiko Kaihara Meidas Lourdes Aparecida Zampieri D'Andrea Francisco Assis Silva Edilson Ferreira Flores Ivete Rocha Anjolete Luiz Euribel Prestes-Carneiro
author_facet	Regiane Soares Santana Karina Briguenti Souza Fernanda Lussari Elivelton Silva Fonseca Cristiane Oliveira Andrade Marcia Mitiko Kaihara Meidas Lourdes Aparecida Zampieri D'Andrea Francisco Assis Silva Edilson Ferreira Flores Ivete Rocha Anjolete Luiz Euribel Prestes-Carneiro
author_sort	Regiane Soares Santana
title	Cases and distribution of visceral leishmaniasis in western São Paulo: A neglected disease in this region of Brazil.
title_short	Cases and distribution of visceral leishmaniasis in western São Paulo: A neglected disease in this region of Brazil.
title_full	Cases and distribution of visceral leishmaniasis in western São Paulo: A neglected disease in this region of Brazil.
title_fullStr	Cases and distribution of visceral leishmaniasis in western São Paulo: A neglected disease in this region of Brazil.
title_full_unstemmed	Cases and distribution of visceral leishmaniasis in western São Paulo: A neglected disease in this region of Brazil.
title_sort	cases and distribution of visceral leishmaniasis in western são paulo: a neglected disease in this region of brazil.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/5b19825ece1b47bb82846c45e888a0c5
work_keys_str_mv	AT regianesoaressantana casesanddistributionofvisceralleishmaniasisinwesternsaopauloaneglecteddiseaseinthisregionofbrazil AT karinabriguentisouza casesanddistributionofvisceralleishmaniasisinwesternsaopauloaneglecteddiseaseinthisregionofbrazil AT fernandalussari casesanddistributionofvisceralleishmaniasisinwesternsaopauloaneglecteddiseaseinthisregionofbrazil AT eliveltonsilvafonseca casesanddistributionofvisceralleishmaniasisinwesternsaopauloaneglecteddiseaseinthisregionofbrazil AT cristianeoliveiraandrade casesanddistributionofvisceralleishmaniasisinwesternsaopauloaneglecteddiseaseinthisregionofbrazil AT marciamitikokaiharameidas casesanddistributionofvisceralleishmaniasisinwesternsaopauloaneglecteddiseaseinthisregionofbrazil AT lourdesaparecidazampieridandrea casesanddistributionofvisceralleishmaniasisinwesternsaopauloaneglecteddiseaseinthisregionofbrazil AT franciscoassissilva casesanddistributionofvisceralleishmaniasisinwesternsaopauloaneglecteddiseaseinthisregionofbrazil AT edilsonferreiraflores casesanddistributionofvisceralleishmaniasisinwesternsaopauloaneglecteddiseaseinthisregionofbrazil AT iveterochaanjolete casesanddistributionofvisceralleishmaniasisinwesternsaopauloaneglecteddiseaseinthisregionofbrazil AT luizeuribelprestescarneiro casesanddistributionofvisceralleishmaniasisinwesternsaopauloaneglecteddiseaseinthisregionofbrazil
_version_	1718413683018694656

Cases and distribution of visceral leishmaniasis in western São Paulo: A neglected disease in this region of Brazil.

Ejemplares similares