PLD1 promotes dendritic spine development by inhibiting ADAM10-mediated N-cadherin cleavage

Abstract Synapses are the basic units of information transmission, processing and integration in the nervous system. Dysfunction of the synaptic development has been recognized as one of the main reasons for mental dementia and psychiatric diseases such as Alzheimer’s disease and autism. However, th...

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Autores principales: Li-Da Luo, Gang Li, Yun Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/5b2b2352d8904f289b2b0189925ce810
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