Broadly Reactive Influenza Antibodies Are Not Limited by Germinal Center Competition with High-Affinity Antibodies

ABSTRACT Enhancing the generation of broadly reactive antibodies against influenza A virus (IAV) is a pertinent goal toward developing a universal IAV vaccine. While antibodies that bind conserved IAV epitopes have been identified in humans, antibodies specific for the variable epitopes are much mor...

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Autores principales: Rachael Keating, Jenny L. Johnson, David C. Brice, Jocelyn G. Labombarde, Alexander L. Dent, Maureen A. McGargill
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
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Acceso en línea:https://doaj.org/article/5b32c45fd4eb4b00b07f17f7bdc5be4e
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