Broadly Reactive Influenza Antibodies Are Not Limited by Germinal Center Competition with High-Affinity Antibodies
ABSTRACT Enhancing the generation of broadly reactive antibodies against influenza A virus (IAV) is a pertinent goal toward developing a universal IAV vaccine. While antibodies that bind conserved IAV epitopes have been identified in humans, antibodies specific for the variable epitopes are much mor...
Saved in:
Main Authors: | Rachael Keating, Jenny L. Johnson, David C. Brice, Jocelyn G. Labombarde, Alexander L. Dent, Maureen A. McGargill |
---|---|
Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2020
|
Subjects: | |
Online Access: | https://doaj.org/article/5b32c45fd4eb4b00b07f17f7bdc5be4e |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Fcγ Receptors Contribute to the Antiviral Properties of Influenza Virus Neuraminidase-Specific Antibodies
by: E. R. Job, et al.
Published: (2019) -
Vaccination with a Recombinant H7 Hemagglutinin-Based Influenza Virus Vaccine Induces Broadly Reactive Antibodies in Humans
by: Daniel Stadlbauer, et al.
Published: (2017) -
OMOLOGICAL AND HETEROLOGICAL ANTIBODY AND T CELL IMMUNE RESPONSES TO LIVE ATTENUATED INFLUENZA VACCINE A (H5N2) AND A (H7N3)
by: A. N. Naykhin, et al.
Published: (2015) -
Broad and Protective Influenza B Virus Neuraminidase Antibodies in Humans after Vaccination and their Clonal Persistence as Plasma Cells
by: Michael S. Piepenbrink, et al.
Published: (2019) -
Induction of cross-reactive antibodies in mice immunized with conserved influenza A virus neuraminidase-derived linear B-cell epitopes
by: I. A. Sychev, et al.
Published: (2021)