Study protocol of RESCUE-ALS: A Phase 2, randomised, double-blind, placebo-controlled study in early symptomatic amyotrophic lateral sclerosis patients to assess bioenergetic catalysis with CNM-Au8 as a mechanism to slow disease progression
Introduction Amyotrophic lateral sclerosis (ALS) is an adult-onset, progressive and universally fatal neurodegenerative disorder. In Europe, Australia and Canada, riluzole is the only approved therapeutic agent for the treatment of ALS, while in the USA, riluzole and edaravone have been approved by...
Saved in:
Main Authors: | William Huynh, Steve Vucic, Parvathi Menon, Austin Rynders, Karen S Ho, Robert Glanzman, Michael T Hotchkin |
---|---|
Format: | article |
Language: | EN |
Published: |
BMJ Publishing Group
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/5b34b89dba1c4672a117a2d5413de1b6 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Rescue of conformational dynamics in enzyme catalysis by directed evolution
by: Renee Otten, et al.
Published: (2018) -
Ketogenesis controls mitochondrial gene expression and rescues mitochondrial bioenergetics after cervical spinal cord injury in rats
by: Oscar Seira, et al.
Published: (2021) - Journal of bioenergetics and biomembranes
-
Editorial: Microbial Bioenergetics
by: Catarina M. Paquete, et al.
Published: (2021) -
Characterization of Mitochondrial Bioenergetics in Preeclampsia
by: Ramana Vaka, et al.
Published: (2021)