Chronic exposure to low doses of estradiol-17ß increases blood pressure in young female rats: A possible role for central Endothelin-1

Chronic exposure to low doses of estradiol-17ß increases blood pressure in young female rats: A possible role for central Endothelin-1

Abstract Previously, we demonstrated that chronic exposure to low levels of estradiol-17β (E2) increases mean arterial pressure (MAP) in young female Sprague-Dawley (SD) rats, however, the underlying mechanisms are unclear. Since endothelin-1 (ET-1) is implicated in blood pressure (BP) regulation, w...

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Bibliographic Details
Main Authors: Madhan Subramanian, Sheba M. J. MohanKumar, Priya Balasubramanian, Carrie A. Northcott, Hannah Garver, Gregory D. Fink, P. S. MohanKumar
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/5b3d84ddcacc44f88325f3307cfad5de
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https://doaj.org/article/5b3d84ddcacc44f88325f3307cfad5de

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