Immunologic mechanisms of seasonal influenza vaccination administered by microneedle patch from a randomized phase I trial

Abstract In a phase 1 randomized, single-center clinical trial, inactivated influenza virus vaccine delivered through dissolvable microneedle patches (MNPs) was found to be safe and immunogenic. Here, we compare the humoral and cellular immunologic responses in a subset of participants receiving inf...

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Autores principales: Nadine G. Rouphael, Lilin Lai, Sonia Tandon, Michele Paine McCullough, Yunchuan Kong, Sarah Kabbani, Muktha S. Natrajan, Yongxian Xu, Yerun Zhu, Dongli Wang, Jesse O’Shea, Amy Sherman, Tianwei Yu, Sebastien Henry, Devin McAllister, Daniel Stadlbauer, Surender Khurana, Hana Golding, Florian Krammer, Mark J. Mulligan, Mark R. Prausnitz
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5b49040c2002496f8128ac3623836663
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