Immunologic mechanisms of seasonal influenza vaccination administered by microneedle patch from a randomized phase I trial
Abstract In a phase 1 randomized, single-center clinical trial, inactivated influenza virus vaccine delivered through dissolvable microneedle patches (MNPs) was found to be safe and immunogenic. Here, we compare the humoral and cellular immunologic responses in a subset of participants receiving inf...
Guardado en:
Autores principales: | Nadine G. Rouphael, Lilin Lai, Sonia Tandon, Michele Paine McCullough, Yunchuan Kong, Sarah Kabbani, Muktha S. Natrajan, Yongxian Xu, Yerun Zhu, Dongli Wang, Jesse O’Shea, Amy Sherman, Tianwei Yu, Sebastien Henry, Devin McAllister, Daniel Stadlbauer, Surender Khurana, Hana Golding, Florian Krammer, Mark J. Mulligan, Mark R. Prausnitz |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/5b49040c2002496f8128ac3623836663 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Local Response to Microneedle-Based Influenza Immunization in the Skin
por: Maria del Pilar Martin, et al.
Publicado: (2012) -
Microneedle patch delivery of influenza vaccine during pregnancy enhances maternal immune responses promoting survival and long-lasting passive immunity to offspring
por: E. Stein Esser, et al.
Publicado: (2017) -
Effect of adjuvants on responses to skin immunization by microneedles coated with influenza subunit vaccine.
por: William C Weldon, et al.
Publicado: (2012) -
Advances of microneedles in hormone delivery
por: Thuy Trang Nguyen, et al.
Publicado: (2022) -
Protein encapsulation in polymeric microneedles by photolithography
por: Kochhar JS, et al.
Publicado: (2012)