Contribution of Lipid Oxidation and Ferroptosis to Radiotherapy Efficacy

Radiotherapy promotes tumor cell death and senescence through the induction of oxidative damage. Recent work has highlighted the importance of lipid peroxidation for radiotherapy efficacy. Excessive lipid peroxidation can promote ferroptosis, a regulated form of cell death. In this review, we addres...

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Détails bibliographiques
Auteurs principaux: Ashley N. Pearson, Joseph Carmicheal, Long Jiang, Yu Leo Lei, Michael D. Green
Format: article
Langue:EN
Publié: MDPI AG 2021
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Accès en ligne:https://doaj.org/article/5b4a7ed5e11a4465a7602a24eee38ea1
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