Dynamin inhibition causes context-dependent cell death of leukemia and lymphoma cells.

Current chemotherapy for treatment of pediatric acute leukemia, although generally successful, is still a matter of concern due to treatment resistance, relapses and life-long side effects for a subset of patients. Inhibition of dynamin, a GTPase involved in clathrin-mediated endocytosis and regulat...

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Autores principales: Christopher von Beek, Linnéa Alriksson, Josefine Palle, Ann-Marie Gustafson, Mirjana Grujic, Fabio Rabelo Melo, Mikael E Sellin, Gunnar Pejler
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/5b614d18e45a4f0386467264e671f2aa
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