Microphthalmia in Texel sheep is associated with a missense mutation in the paired-like homeodomain 3 (PITX3) gene.

Microphthalmia in sheep is an autosomal recessive inherited congenital anomaly found within the Texel breed. It is characterized by extremely small or absent eyes and affected lambs are absolutely blind. For the first time, we use a genome-wide ovine SNP array for positional cloning of a Mendelian t...

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Autores principales: Doreen Becker, Jens Tetens, Adrian Brunner, Daniela Bürstel, Martin Ganter, James Kijas, International Sheep Genomics Consortium, Cord Drögemüller
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/5b63a50765ed4d2f96e31250ad3fe78e
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