Attenuated asthma phenotype in mice with a fetal-like antigen receptor repertoire

Abstract We hypothesized that the scarcity of N-nucleotides might contribute to the inability of the neonate to mount a robust allergic immune response. To test this, we used terminal deoxyribunucleotidyl Transferase deficient (TdT−/−) mice, which express “fetal-like” T cell receptor and immunoglobu...

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Auteurs principaux: Regine Stutz, Christopher Meyer, Elisabeth Kaiser, Sybelle Goedicke-Fritz, Harry W. Schroeder, Robert Bals, Christoph Haertel, Tobias Rogosch, Sebastian Kerzel, Michael Zemlin
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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R
Q
Accès en ligne:https://doaj.org/article/5b8e090760254a5383816ea9541a8604
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