Tubulin binding potentially clears up Bortezomib and Carfilzomib differential neurotoxic effect

Abstract Proteasome inhibitors (PIs) represent the gold standard in the treatment of multiple myeloma. Among PIs, Bortezomib (BTZ) is frequently used as first line therapy, but peripheral neuropathy (PN), occurring approximately in 50% of patients, impairs their life, representing a dose-limiting to...

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Autores principales: A. Malacrida, S. Semperboni, A. Di Domizio, A. Palmioli, L. Broggi, C. Airoldi, C. Meregalli, G. Cavaletti, G. Nicolini
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/5bb52f7cbfd047d0957809e366036543
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